miR-16 rescues F508del-CFTR function in native cystic fibrosis epithelial cells

Cystic fibrosis (CF) is due to mutations in the CFTR gene, which prevents correct folding, trafficking and function of the mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein. The dysfunctional effect of CFTR mutations, principally the F508del-CFTR mutant, is further manifested...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Gene Ther
Egile Nagusiak: Kumar, P, Bhattacharyya, S, Peters, KW, Glover, ML, Sen, A, Cox, RT, Kundu, S, Caohuy, H, Frizzell, RA, Pollard, HB, Biswas, R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488273/
https://ncbi.nlm.nih.gov/pubmed/26133785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2015.56
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