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Galectin-8-N-domain Recognition Mechanism for Sialylated and Sulfated Glycans
Galectin-8 has much higher affinity for 3′-O-sulfated or 3′-O-sialylated glycoconjugates and a Lewis X-containing glycan than for oligosaccharides terminating in Galβ1→3/4GlcNAc, and this specificity is mainly attributed to the N-terminal carbohydrate recognition domain (N-domain, CRD) (Ideo, H., Se...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064191/ https://ncbi.nlm.nih.gov/pubmed/21288902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.195925 |
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