Dual Specificity of Langerin to Sulfated and Mannosylated Glycans via a Single C-type Carbohydrate Recognition Domain

Langerin is categorized as a C-type lectin selectively expressed in Langerhans cells, playing roles in the first line of defense against pathogens and in Birbeck granule formation. Although these functions are thought to be exerted through glycan-binding activity of the C-type carbohydrate recogniti...

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Bibliografiske detaljer
Main Authors: Tateno, Hiroaki, Ohnishi, Koji, Yabe, Rikio, Hayatsu, Norihito, Sato, Takashi, Takeya, Motohiro, Narimatsu, Hisashi, Hirabayashi, Jun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825434/
https://ncbi.nlm.nih.gov/pubmed/20026605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041863
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