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Dual Specificity of Langerin to Sulfated and Mannosylated Glycans via a Single C-type Carbohydrate Recognition Domain

Langerin is categorized as a C-type lectin selectively expressed in Langerhans cells, playing roles in the first line of defense against pathogens and in Birbeck granule formation. Although these functions are thought to be exerted through glycan-binding activity of the C-type carbohydrate recogniti...

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Autori principali: Tateno, Hiroaki, Ohnishi, Koji, Yabe, Rikio, Hayatsu, Norihito, Sato, Takashi, Takeya, Motohiro, Narimatsu, Hisashi, Hirabayashi, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825434/
https://ncbi.nlm.nih.gov/pubmed/20026605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041863
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