Galectin-8-N-domain Recognition Mechanism for Sialylated and Sulfated Glycans

Galectin-8 has much higher affinity for 3′-O-sulfated or 3′-O-sialylated glycoconjugates and a Lewis X-containing glycan than for oligosaccharides terminating in Galβ1→3/4GlcNAc, and this specificity is mainly attributed to the N-terminal carbohydrate recognition domain (N-domain, CRD) (Ideo, H., Se...

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Hlavní autoři: Ideo, Hiroko, Matsuzaka, Tsutomu, Nonaka, Takamasa, Seko, Akira, Yamashita, Katsuko
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064191/
https://ncbi.nlm.nih.gov/pubmed/21288902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.195925
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