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Membrane Anchoring and Interaction between Transmembrane Domains are Crucial for K(+) Channel Function

The small viral channel Kcv is a Kir-like K(+) channel of only 94 amino acids. With this simple structure, the tetramer of Kcv represents the pore module of all complex K(+) channels. To examine the structural contribution of the transmembrane domains (TMDs) to channel function, we performed Ala sca...

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Bibliografische gegevens
Hoofdauteurs: Gebhardt, Manuela, Hoffgaard, Franziska, Hamacher, Kay, Kast, Stefan M., Moroni, Anna, Thiel, Gerhard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064186/
https://ncbi.nlm.nih.gov/pubmed/21310959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211672
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