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Membrane Anchoring and Interaction between Transmembrane Domains are Crucial for K(+) Channel Function
The small viral channel Kcv is a Kir-like K(+) channel of only 94 amino acids. With this simple structure, the tetramer of Kcv represents the pore module of all complex K(+) channels. To examine the structural contribution of the transmembrane domains (TMDs) to channel function, we performed Ala sca...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064186/ https://ncbi.nlm.nih.gov/pubmed/21310959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.211672 |
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