Ncb5or Deficiency Increases Fatty Acid Catabolism and Oxidative Stress

The endoplasmic reticulum-associated NADH cytochrome b(5) oxidoreductase (Ncb5or) is widely distributed in animal tissues. Ncb5or(−/−) mice develop diabetes at age 7 weeks and have increased susceptibility to the diabetogenic oxidant streptozotocin. Ncb5or deficiency also results in lipoatrophy and...

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Hlavní autoři: Xu, Ming, Wang, WenFang, Frontera, Jennifer R., Neely, Melanie C., Lu, Jianghua, Aires, Daniel, Hsu, Fong-Fu, Turk, John, Swerdlow, Russell H., Carlson, Susan E., Zhu, Hao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064168/
https://ncbi.nlm.nih.gov/pubmed/21300801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.196543
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