Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes

OBJECTIVE: During diabetes, retinal microglial cells are activated to release inflammatory cytokines that initiate neuronal loss and blood–retinal barrier breakdown seen in diabetic retinopathy (DR). The mechanism by which diabetes activates microglia to release those inflammatory mediators is uncle...

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Main Authors: Ibrahim, Ahmed S., El-Remessy, Azza B., Matragoon, Suraporn, Zhang, Wenbo, Patel, Yogin, Khan, Sohail, Al-Gayyar, Mohammed M., El-Shishtawy, Mamdouh M., Liou, Gregory I.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2011
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064086/
https://ncbi.nlm.nih.gov/pubmed/21317295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1160
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