Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes

OBJECTIVE: During diabetes, retinal microglial cells are activated to release inflammatory cytokines that initiate neuronal loss and blood–retinal barrier breakdown seen in diabetic retinopathy (DR). The mechanism by which diabetes activates microglia to release those inflammatory mediators is uncle...

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Detalhes bibliográficos
Main Authors: Ibrahim, Ahmed S., El-Remessy, Azza B., Matragoon, Suraporn, Zhang, Wenbo, Patel, Yogin, Khan, Sohail, Al-Gayyar, Mohammed M., El-Shishtawy, Mamdouh M., Liou, Gregory I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064086/
https://ncbi.nlm.nih.gov/pubmed/21317295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1160
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