Thioredoxin interacting protein is a novel mediator of retinal inflammation and neurotoxicity

BACKGROUND AND PURPOSE: Up-regulation of thioredoxin interacting protein (TXNIP), an endogenous inhibitor of thioredoxin (Trx), compromises cellular antioxidant and anti-apoptotic defences and stimulates pro-inflammatory cytokines expression, implying a role for TXNIP in apoptosis. Here we have exam...

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Bibliografische gegevens
Hoofdauteurs: Al-Gayyar, Mohammed MH, Abdelsaid, Mohammed A, Matragoon, Suraporn, Pillai, Bindu A, El-Remessy, Azza B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Publishing Ltd 2011
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Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171869/
https://ncbi.nlm.nih.gov/pubmed/21434880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01336.x
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