Premature death and neurologic abnormalities in transgenic mice expressing a mutant huntingtin exon-2 fragment

Lignende værker

• Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative
  af: Tebbenkamp, Andrew T.N., et al.
  Udgivet: (2011)
• Transgenic Mouse Model Expressing the Caspase 6 Fragment of Mutant Huntingtin
  af: Waldron-Roby, Elaine, et al.
  Udgivet: (2012)
• Bifunctional Anti-Huntingtin Proteasome-Directed Intrabodies Mediate Efficient Degradation of Mutant Huntingtin Exon 1 Protein Fragments
  af: Butler, David C., et al.
  Udgivet: (2011)
• Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease
  af: Landles, Christian, et al.
  Udgivet: (2010)
• Cytotoxicity of Mutant Huntingtin Fragment in Yeast Can Be Modulated by the Expression Level of Wild Type Huntingtin Fragment
  af: Saleh, Aliabbas Ahmedbhai, et al.
  Udgivet: (2013)