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Fragmented mitochondria are sensitized to Bax insertion and activation during apoptosis

Recent studies have shown mitochondrial fragmentation during cell stress and have suggested a role for the morphological change in mitochondrial injury and ensuing apoptosis. However, the underlying mechanism remains elusive. Here we demonstrate that mitochondrial fragmentation facilitates Bax inser...

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Detalhes bibliográficos
Main Authors: Brooks, Craig, Cho, Sung-Gyu, Wang, Cong-Yi, Yang, Tianxin, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063970/
https://ncbi.nlm.nih.gov/pubmed/21160028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00402.2010
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