Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans

Zinc is an essential trace element involved in a wide range of biological processes and human diseases. Zinc excess is deleterious, and animals require mechanisms to protect against zinc toxicity. To identify genes that modulate zinc tolerance, we performed a forward genetic screen for Caenorhabditi...

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Autors principals: Murphy, John T., Bruinsma, Janelle J., Schneider, Daniel L., Collier, Sara, Guthrie, James, Chinwalla, Asif, Robertson, J. David, Mardis, Elaine R., Kornfeld, Kerry
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063764/
https://ncbi.nlm.nih.gov/pubmed/21455490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002013
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