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ttm-1 Encodes CDF Transporters That Excrete Zinc from Intestinal Cells of C. elegans and Act in a Parallel Negative Feedback Circuit That Promotes Homeostasis

Zinc is an essential metal involved in a wide range of biological processes, and aberrant zinc metabolism is implicated in human diseases. The gastrointestinal tract of animals is a critical site of zinc metabolism that is responsible for dietary zinc uptake and distribution to the body. However, th...

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Detalhes bibliográficos
Main Authors: Roh, Hyun Cheol, Collier, Sara, Deshmukh, Krupa, Guthrie, James, Robertson, J. David, Kornfeld, Kerry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662639/
https://ncbi.nlm.nih.gov/pubmed/23717214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003522
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