The DAF-16 FOXO Transcription Factor Regulates natc-1 to Modulate Stress Resistance in Caenorhabditis elegans, Linking Insulin/IGF-1 Signaling to Protein N-Terminal Acetylation

The insulin/IGF-1 signaling pathway plays a critical role in stress resistance and longevity, but the mechanisms are not fully characterized. To identify genes that mediate stress resistance, we screened for C. elegans mutants that can tolerate high levels of dietary zinc. We identified natc-1, whic...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Warnhoff, Kurt, Murphy, John T., Kumar, Sandeep, Schneider, Daniel L., Peterson, Michelle, Hsu, Simon, Guthrie, James, Robertson, J. David, Kornfeld, Kerry
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199503/
https://ncbi.nlm.nih.gov/pubmed/25330323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004703
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares