The DAF-16 FOXO Transcription Factor Regulates natc-1 to Modulate Stress Resistance in Caenorhabditis elegans, Linking Insulin/IGF-1 Signaling to Protein N-Terminal Acetylation

The insulin/IGF-1 signaling pathway plays a critical role in stress resistance and longevity, but the mechanisms are not fully characterized. To identify genes that mediate stress resistance, we screened for C. elegans mutants that can tolerate high levels of dietary zinc. We identified natc-1, whic...

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Detaylı Bibliyografya
Asıl Yazarlar: Warnhoff, Kurt, Murphy, John T., Kumar, Sandeep, Schneider, Daniel L., Peterson, Michelle, Hsu, Simon, Guthrie, James, Robertson, J. David, Kornfeld, Kerry
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199503/
https://ncbi.nlm.nih.gov/pubmed/25330323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004703
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