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Identification of Mutations in Caenorhabditis elegans That Cause Resistance to High Levels of Dietary Zinc and Analysis Using a Genomewide Map of Single Nucleotide Polymorphisms Scored by Pyrosequencing

Zinc plays many critical roles in biological systems: zinc bound to proteins has structural and catalytic functions, and zinc is proposed to act as a signaling molecule. Because zinc deficiency and excess result in toxicity, animals have evolved sophisticated mechanisms for zinc metabolism and homeo...

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Bibliografiske detaljer
Main Authors: Bruinsma, Janelle J., Schneider, Daniel L., Davis, Diana E., Kornfeld, Kerry
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429876/
https://ncbi.nlm.nih.gov/pubmed/18505880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.084384
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