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Next Generation Hairpin Polyamides with (R)-3,4-Diaminobutyric Acid Turn Unit

The characterization of a new class of pyrrole–imidazole hairpin polyamides with β-amino-γ-turn units for recognition of the DNA minor groove is reported. A library of eight hairpins containing (R)-and (S)-3,4-diaminobutyric acid (β-amino-γ-turn) has been synthesized, and the impact of the molecules...

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Bibliografiska uppgifter
Huvudupphovsmän: Dose, Christian, Farkas, Michelle E., Chenoweth, David M., Dervan, Peter B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063708/
https://ncbi.nlm.nih.gov/pubmed/18459783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja800888d
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