Tissue-specific expression of the human alpha 1-antitrypsin gene is controlled by multiple cis-regulatory elements.
Human alpha 1-antitrypsin (AAT) is expressed in the liver, and a 318 bp fragment immediately flanking the CAP site of the gene was found to be sufficient to drive the expression of a reporter gene (CAT) specifically in hepatoma cells. The enhancing activity however, was orientation-dependent. The DN...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1987
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306367/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2823229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.20.8399 |
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