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Comparison of Constitutional and Replication Stress-Induced Genome Structural Variation by SNP Array and Mate-Pair Sequencing

Copy-number variants (CNVs) are a major source of genetic variation in human health and disease. Previous studies have implicated replication stress as a causative factor in CNV formation. However, existing data are technically limited in the quality of comparisons that can be made between human CNV...

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Main Authors: Arlt, Martin F., Ozdemir, Alev Cagla, Birkeland, Shanda R., Lyons, Robert H., Glover, Thomas W., Wilson, Thomas E.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063664/
https://ncbi.nlm.nih.gov/pubmed/21212237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.124776
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