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Discovery of Mutations in Saccharomyces cerevisiae by Pooled Linkage Analysis and Whole-Genome Sequencing

Many novel and important mutations arise in model organisms and human patients that can be difficult or impossible to identify using standard genetic approaches, especially for complex traits. Working with a previously uncharacterized dominant Saccharomyces cerevisiae mutant with impaired vacuole in...

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Main Authors: Birkeland, Shanda R., Jin, Natsuko, Ozdemir, Alev Cagla, Lyons, Robert H., Weisman, Lois S., Wilson, Thomas E.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998298/
https://ncbi.nlm.nih.gov/pubmed/20923977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.123232
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