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Discovery of Mutations in Saccharomyces cerevisiae by Pooled Linkage Analysis and Whole-Genome Sequencing

Many novel and important mutations arise in model organisms and human patients that can be difficult or impossible to identify using standard genetic approaches, especially for complex traits. Working with a previously uncharacterized dominant Saccharomyces cerevisiae mutant with impaired vacuole in...

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Detalhes bibliográficos
Main Authors: Birkeland, Shanda R., Jin, Natsuko, Ozdemir, Alev Cagla, Lyons, Robert H., Weisman, Lois S., Wilson, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998298/
https://ncbi.nlm.nih.gov/pubmed/20923977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.123232
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