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Guanine modification during chemical DNA synthesis.
Base modification during solid-phase phosphoramidite synthesis of oligodeoxynucleotides has been investigated. We have discovered chemical modification that converts dG and dG-containing oligomers to a fluorescent form. This modification has been linked to N,N-dimethylaminopyridine (DMAP), an acylat...
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| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1987
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306363/ https://ncbi.nlm.nih.gov/pubmed/3671086 |
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