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Guanine modification during chemical DNA synthesis.

Base modification during solid-phase phosphoramidite synthesis of oligodeoxynucleotides has been investigated. We have discovered chemical modification that converts dG and dG-containing oligomers to a fluorescent form. This modification has been linked to N,N-dimethylaminopyridine (DMAP), an acylat...

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Detalhes bibliográficos
Main Authors: Eadie, J S, Davidson, D S
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC306363/
https://ncbi.nlm.nih.gov/pubmed/3671086
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