Synthesis and Characterization of PEGylated Toll Like Receptor 7 Ligands

Toll like receptor 7 (TLR7) is located in the endosomal compartment of immune cells. Signaling through TLR7, mediated by the adaptor protein MyD88, stimulates the innate immune system and shapes adaptive immune responses. Previously, we characterized TLR7 ligands conjugated to protein, lipid or poly...

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Hauptverfasser: Chan, Michael, Hayashi, Tomoko, Mathewson, Richard D., Yao, Shiyin, Gray, Christine, Tawatao, Rommel, Kalenian, Kevin, Zhang, Yanmei, Hayashi, Yuki, Lao, Fitzgerald S., Cottam, Howard B., Carson, Dennis A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063487/
https://ncbi.nlm.nih.gov/pubmed/21338093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc1004813
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