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Highly Activated Cytotoxic CD8 T Cells Express Protective IL-10 At The Peak Of Coronavirus-induced Encephalitis
Acute viral encephalitis requires rapid pathogen elimination without significant bystander tissue damage. Here, we show that IL-10, a potent anti-inflammatory cytokine, is produced transiently at the peak of infection by CD8 T cells in the brains of coronavirus-infected mice. IL-10(+)CD8 and IL-10(−...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063297/ https://ncbi.nlm.nih.gov/pubmed/21317392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003292 |
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