Loading...

Regulatory T cells inhibit T cell proliferation and decrease demyelination in mice chronically infected with a coronavirus

Mice infected with the neurotropic JHM strain of mouse hepatitis virus (JHMV) develop acute and chronic demyelinating diseases with histopathological similarities to MS. The process of demyelination is largely immune-mediated, as immunodeficient mice (RAG1(−/−) mice) do not develop demyelination upo...

Full description

Saved in:
Bibliographic Details
Main Authors: Trandem, Kathryn, Anghelina, Daniela, Zhao, Jingxian, Perlman, Stanley
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851486/
https://ncbi.nlm.nih.gov/pubmed/20208000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903918
Tags: Add Tag
No Tags, Be the first to tag this record!