Expression of DDX3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells

DEAD box protein, DDX3, is aberrantly expressed in breast cancer cells ranging from weakly invasive to aggressive phenotypes and functions as an important regulator of cancer cell growth and survival. Here, we demonstrate that hypoxia inducible factor-1α is a transcriptional activator of DDX3 in bre...

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Bibliografiske detaljer
Main Authors: Botlagunta, Mahendran, Krishnamachary, Balaji, Vesuna, Farhad, Winnard, Paul T., Bol, Guus M., Patel, Arvind H., Raman, Venu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063174/
https://ncbi.nlm.nih.gov/pubmed/21448281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017563
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