Expression of DDX3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells

DEAD box protein, DDX3, is aberrantly expressed in breast cancer cells ranging from weakly invasive to aggressive phenotypes and functions as an important regulator of cancer cell growth and survival. Here, we demonstrate that hypoxia inducible factor-1α is a transcriptional activator of DDX3 in bre...

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Detalhes bibliográficos
Main Authors: Botlagunta, Mahendran, Krishnamachary, Balaji, Vesuna, Farhad, Winnard, Paul T., Bol, Guus M., Patel, Arvind H., Raman, Venu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063174/
https://ncbi.nlm.nih.gov/pubmed/21448281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017563
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