Expression of the RNA Helicase DDX3 and the Hypoxia Response in Breast Cancer

AIMS: DDX3 is an RNA helicase that has antiapoptotic properties, and promotes proliferation and transformation. In addition, DDX3 was shown to be a direct downstream target of HIF-1α (the master regulatory of the hypoxia response) in breast cancer cell lines. However, the relation between DDX3 and h...

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Main Authors: Bol, Guus M., Raman, Venu, van der Groep, Petra, Vermeulen, Jeroen F., Patel, Arvind H., van der Wall, Elsken, van Diest, Paul J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656050/
https://ncbi.nlm.nih.gov/pubmed/23696831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063548
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