Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer

PURPOSE: DEAD box protein 3 (DDX3) is an RNA helicase with oncogenic properties that shuttles between the cytoplasm and nucleus. The majority of DDX3 is found in the cytoplasm, but a subset of tumors has distinct nuclear DDX3 localization of yet unknown biological significance. This study aimed to e...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Heerma van Voss, Marise R, Vesuna, Farhad, Bol, Guus M, Meeldijk, Jan, Raman, Ana, Offerhaus, G Johan, Buerger, Horst, Patel, Arvind H, van der Wall, Elsken, van Diest, Paul J, Raman, Venu
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522823/
https://ncbi.nlm.nih.gov/pubmed/28761359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S140639
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