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Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer

Identifying druggable targets in the Wnt-signaling pathway can optimize colorectal cancer treatment. Recent studies have identified a member of the RNA helicase family DDX3 (DDX3X) as a multilevel activator of Wnt signaling in cells without activating mutations in the Wnt-signaling pathway. In this...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: van Voss, Marise R. Heerma, Vesuna, Farhad, Trumpi, Kari, Brilliant, Justin, Berlinicke, Cynthia, de Leng, Wendy, Kranenburg, Onno, Offerhaus, Johan G., Bürger, Horst, van der Wall, Elsken, van Diest, Paul J., Raman, Venu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695062/
https://ncbi.nlm.nih.gov/pubmed/26311743
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