Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer

Identifying druggable targets in the Wnt-signaling pathway can optimize colorectal cancer treatment. Recent studies have identified a member of the RNA helicase family DDX3 (DDX3X) as a multilevel activator of Wnt signaling in cells without activating mutations in the Wnt-signaling pathway. In this...

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Gardado en:
Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: van Voss, Marise R. Heerma, Vesuna, Farhad, Trumpi, Kari, Brilliant, Justin, Berlinicke, Cynthia, de Leng, Wendy, Kranenburg, Onno, Offerhaus, Johan G., Bürger, Horst, van der Wall, Elsken, van Diest, Paul J., Raman, Venu
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695062/
https://ncbi.nlm.nih.gov/pubmed/26311743
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