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Silencing Kinase Interacting Stathmin Gene Enhances Erlotinib Sensitivity by Inhibiting Serine 10 p27 Phosphorylation in EGFR-expressing Breast Cancer
The epidermal growth factor receptor (EGFR) signaling pathway has emerged as a promising target for cancer therapy. EGFR tyrosine kinase inhibitors (TKIs) such as erlotinib have been approved for cancer treatment but have demonstrated very limited activity in breast cancer patients. Clarifying the m...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062953/ https://ncbi.nlm.nih.gov/pubmed/21045138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0362 |
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