EGFR Tyrosine Kinase Inhibitor Reverses Mesenchymal to Epithelial Phenotype and Inhibits Metastasis in Inflammatory Breast Cancer

PURPOSE: Inflammatory breast cancer (IBC) is a rare but aggressive type of advanced breast cancer. Epidermal growth factor receptor (EGFR) expression is an independent poor prognostic factor in IBC. The purpose of this study was to determine the impact on IBC tumorigenicity and metastasis of blockin...

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Detalhes bibliográficos
Main Authors: Zhang, Dongwei, LaFortune, Tiffany A., Krishnamurthy, Savitri, Esteva, Francisco J., Cristofanilli, Massimo, Liu, Ping, Lucci, Anthony, Singh, Balraj, Hung, Mien-Chie, Hortobagyi, Gabriel N., Ueno, Naoto T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783487/
https://ncbi.nlm.nih.gov/pubmed/19825949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0951
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