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Immunogenicity of protein therapeutics: The key causes, consequences and challenges

The immunogenicity of protein therapeutics has so far proven to be difficult to predict in patients, with many biologics inducing undesirable immune responses directed towards the therapeutic resulting in reduced efficacy, anaphylaxis and occasionally life threatening autoimmunity. The most common e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Baker, Matthew P, Reynolds, Helen M, Lumicisi, Brooke, Bryson, Christine J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062386/
https://ncbi.nlm.nih.gov/pubmed/21487506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.1.4.13904
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