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Immunogenicity of protein therapeutics: The key causes, consequences and challenges
The immunogenicity of protein therapeutics has so far proven to be difficult to predict in patients, with many biologics inducing undesirable immune responses directed towards the therapeutic resulting in reduced efficacy, anaphylaxis and occasionally life threatening autoimmunity. The most common e...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3062386/ https://ncbi.nlm.nih.gov/pubmed/21487506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.1.4.13904 |
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