HIV disease progression correlates with the generation of dysfunctional naive CD8(low) T cells

HIV infection can result in depletion of total CD4(+) T cells and naive CD8(+) T cells, and in the generation of dysfunctional effector CD8(+) T cells. In this study, we show that naive CD8(+) T cells in subjects with progressive HIV disease express low levels of CD8α and CD8β chains. Such naive CD8...

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Bibliografiska uppgifter
Huvudupphovsmän: Favre, David, Stoddart, Cheryl A., Emu, Brinda, Hoh, Rebecca, Martin, Jeffrey N., Hecht, Frederick M., Deeks, Steven G., McCune, Joseph M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2011
Ämnen:
Immunobiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062328/
https://ncbi.nlm.nih.gov/pubmed/21200021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-288035
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