IL-2 production correlates with effector cell differentiation in HIV-specific CD8+ T cells

BACKGROUND: Diminished IL-2 production and lack of effector differentiation have been reported for HIV-specific T cells. In this study, we examined the prevalence of these phenomena using 8-color cytokine flow cytometry, and tested the hypothesis that these two findings were causally related. We ana...

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Autors principals: Nomura, Laurel E, Emu, Brinda, Hoh, Rebecca, Haaland, Perry, Deeks, Steven G, Martin, Jeffrey N, McCune, Joseph M, Nixon, Douglas F, Maecker, Holden T
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1562434/
https://ncbi.nlm.nih.gov/pubmed/16859558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-3-18
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