CD8(+)CD44(hi) but not CD4(+)CD44(hi) memory T cells mediate potent graft antilymphoma activity without GVHD

Allogeneic hematopoietic cell transplantation can be curative in patients with leukemia and lymphoma. However, progressive growth of malignant cells, relapse after transplantation, and graft-versus-host disease (GVHD) remain important problems. The goal of the current murine study was to select a fr...

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Bibliografiske detaljer
Main Authors: Dutt, Suparna, Baker, Jeanette, Kohrt, Holbrook E., Kambham, Neeraja, Sanyal, Mrinmoy, Negrin, Robert S., Strober, Samuel
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Transplantation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062320/
https://ncbi.nlm.nih.gov/pubmed/21239702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-312751
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