Human DNA (cytosine-5)methyltransferase selectively methylates duplex DNA containing mispairs.
The presence of the C.C mispair in a defined duplex oligodeoxynucleotide enhanced its capacity to serve as a substrate for highly purified human DNA methyltransferase. Analysis of tritiated reaction products showed that the C.C mispair acted as a "methylation acceptor" in that it was itself rapidly...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1987
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306183/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3658670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.17.6899 |
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