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Human DNA (cytosine-5)methyltransferase selectively methylates duplex DNA containing mispairs.
The presence of the C.C mispair in a defined duplex oligodeoxynucleotide enhanced its capacity to serve as a substrate for highly purified human DNA methyltransferase. Analysis of tritiated reaction products showed that the C.C mispair acted as a "methylation acceptor" in that it was itsel...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1987
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306183/ https://ncbi.nlm.nih.gov/pubmed/3658670 |
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