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Human DNA (cytosine-5)methyltransferase selectively methylates duplex DNA containing mispairs.

The presence of the C.C mispair in a defined duplex oligodeoxynucleotide enhanced its capacity to serve as a substrate for highly purified human DNA methyltransferase. Analysis of tritiated reaction products showed that the C.C mispair acted as a "methylation acceptor" in that it was itself rapidly...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Smith, S S, Hardy, T A, Baker, D J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 1987
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306183/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3658670/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.17.6899
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