The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [(1)H]-MRS

The NMDA receptor antagonist ketamine can induce a rapid improvement in depressive symptoms that often endures for days after a single intravenous dose. The pharmacodynamic basis for this effect is poorly understood. Using a proton magnetic resonance spectroscopy ([(1)H]-MRS) method that previously...

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Bibliographic Details
Main Authors: Valentine, Gerald W., Mason, Graeme F., Gomez, Rosane, Fasula, Madonna, Watzl, June, Pittman, Brian, Krystal, John H., Sanacora, Gerard
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061550/
https://ncbi.nlm.nih.gov/pubmed/21232924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pscychresns.2010.10.009
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