Intravenous ethanol infusion decreases human cortical GABA and NAA as measured with (1)H-MRS at 4T

BACKGROUND: Ethanol modulates glutamate and GABA function. However, little is known about the acute pharmacologic effects of ethanol on levels of GABA, glutamate, and other metabolites measurable in the human cortex in vivo using (1)H magnetic resonance spectroscopy (MRS). METHODS: Eleven healthy so...

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Autors principals: Gomez, Rosane, Behar, Kevin L., Watzl, June, Weinzimer, Stuart A., Gulanski, Barbara, Sanacora, Gerard, Koretski, Julia, Guidone, Elizabeth, Jiang, Lihong, Petrakis, Ismene L., Pittman, Brian, Krystal, John H., Mason, Graeme F
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227760/
https://ncbi.nlm.nih.gov/pubmed/21855054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.06.026
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