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Site-Directed Mutations near Transmembrane Domain 1 Alter Conformation and Function of Norepinephrine and Dopamine Transporters
The human dopamine and norepinephrine transporters (hDAT and hNET, respectively) control neurotransmitter levels within the synaptic cleft and are the site of action for amphetamine (AMPH) and cocaine. We investigated the role of a threonine residue within the highly conserved and putative phosphory...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061360/ https://ncbi.nlm.nih.gov/pubmed/21149640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.069039 |
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