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Cutting Edge: Delay and Reversal of T Cell Tolerance by Intratumoral Injection of Antigen-Loaded Dendritic Cells in an Autochthonous Tumor Model

The tumor environment exerts a powerful suppressive influence on infiltrating tumor-reactive T cells. It induces tolerance of adoptively transferred effector T cells as they enter tumors and maintains the tolerance of persisting tumor-infiltrating T cells. In an autochthonous prostate cancer model,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Higham, Eileen M., Shen, Ching-Hung, Wittrup, K. Dane, Chen, Jianzhu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061230/
https://ncbi.nlm.nih.gov/pubmed/20427765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000265
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