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Direct involvement of the TEN domain at the active site of human telomerase
Telomerase is a ribonucleoprotein that adds DNA to the ends of chromosomes. The catalytic protein subunit of telomerase (TERT) contains an N-terminal domain (TEN) that is important for activity and processivity. Here we describe a mutation in the TEN domain of human TERT that results in a greatly in...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061064/ https://ncbi.nlm.nih.gov/pubmed/21051362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1083 |
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