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Direct observation of nucleic acid binding dynamics by the telomerase essential N-terminal domain
Telomerase is a specialized enzyme that maintains telomere length by adding DNA repeats to chromosome ends. The catalytic protein subunit of telomerase utilizes the integral telomerase RNA to direct telomere DNA synthesis. The telomerase essential N-terminal (TEN) domain is required for enzyme funct...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5887506/ https://ncbi.nlm.nih.gov/pubmed/29474579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky117 |
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