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Direct observation of nucleic acid binding dynamics by the telomerase essential N-terminal domain

Telomerase is a specialized enzyme that maintains telomere length by adding DNA repeats to chromosome ends. The catalytic protein subunit of telomerase utilizes the integral telomerase RNA to direct telomere DNA synthesis. The telomerase essential N-terminal (TEN) domain is required for enzyme funct...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Shastry, Shankar, Steinberg-Neifach, Olga, Lue, Neal, Stone, Michael D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887506/
https://ncbi.nlm.nih.gov/pubmed/29474579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky117
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