Llwytho...

Longitudinal Behavioral, Cross-sectional Transcriptional and Histopathological Characterization of a Knock-in Mouse Model of Huntington's Disease with 140 CAG Repeats

The discovery of the gene mutation responsible for Huntington's Disease (HD), huntingtin, in 1993 allowed for a better understanding of the pathology of the and enabled development of animal models. HD is caused by the expansion of a polyglutamine repeat region in the N-terminal of the huntingt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rising, Aaron C., Xu, Jia, Napoli, Vincent V., Carlson, Aaron, Denovan-Wright, Eileen M., Mandel, Ronald J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060971/
https://ncbi.nlm.nih.gov/pubmed/21192926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.12.017
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