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Instability of CAG repeats in Huntington's disease: relation to parental transmission and age of onset.

Huntington's disease (HD) has recently been found to be caused by expansion of a trinucleotide (CAG) repeat within the putative coding region of a gene with an unknown function. We report here an analysis of HD mutation and the characteristics of its transmission in 36 HD families. CAG repeats...

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Bibliografske podrobnosti
Main Authors: Trottier, Y, Biancalana, V, Mandel, J L
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1049869/
https://ncbi.nlm.nih.gov/pubmed/8064815
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