טוען...
Longitudinal Behavioral, Cross-sectional Transcriptional and Histopathological Characterization of a Knock-in Mouse Model of Huntington's Disease with 140 CAG Repeats
The discovery of the gene mutation responsible for Huntington's Disease (HD), huntingtin, in 1993 allowed for a better understanding of the pathology of the and enabled development of animal models. HD is caused by the expansion of a polyglutamine repeat region in the N-terminal of the huntingt...
שמור ב:
| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060971/ https://ncbi.nlm.nih.gov/pubmed/21192926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2010.12.017 |
| תגים: |
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